Scientists are getting close to proving what Yoga Scientists have held to be true for thousands of years: meditation can ward off stress and disease. John Denninger, a psychiatrist at Harvard Medical School, is leading a five-year study on how the ancient practices affect genes and brain activity in the chronically stressed. His latest work follows a study he and others published in 2014 showing how mind- body techniques can switch on and off some genes linked to stress and immune function. While hundreds of studies have been conducted on the mental health benefits of meditation and yoga, they have tended to rely on blunt tools like participant questionnaires, as well as heart rate and blood pressure monitoring. Only in the past few years have neuro-imaging and genomics technology used in Denninger’s latest studies allowed scientists to measure physiological changes in greater detail. “There is a true biological effect,” said Denninger. “The kinds of things that happen when you meditate do have effects throughout the body, not just in the brain.”

This new study may persuade more doctors to try an alternative route for tackling the source of many modern ailments. Stress-induced conditions can include everything from hypertension and infertility to depression and even the aging process. They account for 60 to 90 percent of doctor’s visits in the U.S., according to the Benson-Henry Institute. The World Health Organization estimates stress costs U.S. companies at least $300 billion a year through absenteeism, turn-over and low productivity.